赵婷婷课题组
赵婷婷,博士,中日友好医院临床医学研究所副研究员,协和医科大学、北京医科大学和首都医科大学硕士生导师。曾于2012-2013年赴香港中文大学李嘉诚健康研究所访问,于2017.09-12赴美国耶鲁大学肾脏病系访问。
先后主持科技部重大新药创制课题1项、国家自然科学基金项目4项,北京市自然科学基金面上项目2项、人社部留学回国人员科技活动项目1项等。作为副主编出版专著《糖尿病肾病中西医结合诊疗与研究》,参编专著1部,发表学术论文50余篇,其中SCI论文26篇,先后获得国家科技进步二等奖1项,省部级以上学术奖励奖4项,兼任Integrative Medicine in Nephrology and Andrology编委,国家自然科学基金同行评议专家、中国中西医结合学会肾脏病专业委员会青年委员,中华中医药学会中药实验药理分会青年委员、世界中联肾病专业委员会第三届理事会理事等社会职务。
研究方向
1.中药治疗慢性肾脏病机制研究和新药研发
2.肠道微生物参与糖尿病肾病机制研究
3.医用增塑剂安全性评价研究
合作或招生需求:
1.常年招收基础医学、病理生理学、中西医结合基础、药理学等相关专业联合培养研究生。
2.研究生对科研有较强的兴趣,勤奋努力,具有良好的沟通能力。
联系方式:ttfrfr@163.com
出版专著
1、《糖尿病肾病中西医结合诊疗与研究》李平、谢院生主编,赵婷婷副主编,中国医药科技出版社,2018
代表性学术论文
1、Wang S, Li X, Zhang B, Li Y, Chen K, Qi H, Gao M, Rong J, Liu L, Wan Y, Dong X, Yan M, Ma L, Li P*, Zhao T*(赵婷婷,共同通讯). Tangshen formula targets the gut microbiota to treat non-alcoholic fatty liver disease in HFD mice: A 16S rRNA and non-targeted metabolomics analyses. Biomed Pharmacother. 2024 Apr;173:116405. doi: 10.1016/j.biopha.2024.116405.
2、Gao M#, Zhao T#(赵婷婷,共同一作), Zhang C#, Li P#, Wang J, Han J, Zhang N, Pang B, Liu S. Ferritinophagy-mediated iron competition in RUTIs: Tug-of-war between UPEC and host. Biomed Pharmacother. 2023 Jul;163:114859. doi: 10.1016/j.biopha.2023.114859.
3、Wan Y, Wang S, Chen K, Liu L, Wang X, Zhang B, Hu L, Liu S, Zhao T*. (赵婷婷,共同通讯), Qi H*. High-sulfated derivative of polysaccharide from Ulva pertusa improves Adriamycin-induced nephrotic syndrome by suppressing oxidative stress. Food Funct. 2023 Sep 18. doi: 10.1039/d3fo01290e.
4、Wang S, Zhang B, Chang X, Zhao H, Zhang H, Zhao T*. (赵婷婷,共同通讯), Qi H*. Potential use of seaweed polysaccharides as prebiotics for management of metabolic syndrome: a review. Crit Rev Food Sci Nutr. 2023 Mar 27:1-21.
5、Zhao T(赵婷婷), Zhou Q. Editorial: Molecular Pathophysiology of Diabetes-Related Organ Injury. Front Med (Lausanne). 2022 Mar 18;9:875444. doi: 10.3389/fmed.2022.875444.
6、Wan Y, Liu L, Zhang B, Wang S, Wang X, Chen K, Li Y, Zhao T*. (赵婷婷,共同通讯), Qi H*. Structural Characterization and Anti-Nonalcoholic Fatty Liver Effect of High-Sulfated Ulva pertusa Polysaccharide. Pharmaceuticals (Basel). 2022 Dec 31;16(1):62.
7、Zhang B, Wan Y, Zhou X, Zhang H, Zhao H, Ma L, Dong X, Yan M, Zhao T*. (赵婷婷,共同通讯) and Li P* (2022) Characteristics of Serum Metabolites and Gut Microbiota in Diabetic Kidney Disease. Front. Pharmacol. 13:872988.
8、Hu L, Wang Y, Wan Y, Ma L, Zhao T*. (赵婷婷,共同通讯), Li P*. Tangshen Formula Improves Diabetes-Associated Myocardial Fibrosis by Inhibiting TGF-β/Smads and Wnt/β-Catenin Pathways. Front Med (Lausanne). 2021;8:732042.
9、Zhao T T(赵婷婷), Zhang H J, Yin XB, Zhao HL, Yan MH, Peng L, Wang Q, Dong X, Li P. Tangshen formula modulates gut Microbiota and reduces gut-derived toxins in diabetic nephropathy rats. Biomedicine &Pharmacotherapy 2020, 129, 110325.
10、Li X, Li X, Zhang Q*, Zhao T*. (赵婷婷,共同通讯). Low molecular weight fucoidan and its fractions inhibit renalepithelial mesenchymal transition induced by TGF-1 or FGF-2. International Journal of Biological Macromolecules. 2017, Pt2(105): 1482-1490.
11、Wang Q, Tian X, Zhou W, Wang Y, Zhao H, Li J, Zhou X, Zhang H, Zhao T*. (赵婷婷,共同通讯 ), &Li P*. (2020). Protective Role of Tangshen Formula on the Progression of Renal Damage in db/db Mice by TRPC6/Talin1 Pathway in Podocytes. Journal of diabetes research, 2020, 3634974.17
12、Wang Q, Tian X, Wang Y, Zhao T(赵婷婷,共同通讯)*, Ping Li*. Role of Transient Receptor Potential Canonical Channel 6 (TRPC6) in Diabetic Kidney Disease by Regulating Podocyte Actin Cytoskeleton Rearrangement. Journal of Diabetes Research. 2020,2020:6897390.
13、Han J, Wang X, Hou J, Liu Y, Liu P, Zhao T*( 赵婷婷 ). Using Network Pharmacology to Explore the Mechanism of Peach Kernel-Safflower in the Treatment of Diabetic Nephropathy. Biomed Res Int. 2021 Feb 1;2021:6642584.
14、Liu Y, Chen DQ, Han JX, Zhao TT*(赵婷婷,共同通讯), Li SJ*. A Review of Traditional Chinese Medicine in Treating Renal Interstitial Fibrosis via Endoplasmic Reticulum Stress-Mediated Apoptosis. Biomed Res Int. 2021 May 15;2021:6667791.
15、Yao Y, Yu YC, Cai MR, Zhang ZQ, Bai J, Wu HM, Li P, Zhao TT*(赵婷婷,共同通讯), Ni J*, Yin XB*. UPLC-MS/MS method for the determination of the herb composition of Tangshen formula and the in vivo pharmacokinetics of its metabolites in rat plasma. Phytochem Anal. 2022, 33(3):402-426.
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